The Opportunity:

Cancer Grand Challenges from DNA damage to the mechanisms of mutagenesis

We are looking to employ a post-doctoral researcher to join the group of Professor Martin Taylor at the Institute of Genetics and Cancer (IGC), working to understand the mechanisms that drive mutagenesis. In this post you will be a key member of the international Cancer Grand Challenges CAUSE team mechanistically relating DNA damage to the mutations it generates. This is pioneering research in a highly collaborative international team embedded within a well-supported, collegiate and enthusiastic research group.

This specific role is will drive the development and application of technologies to enrich for and map DNA damage and modifications within the human genome. You will explore how that damage is processed leading to repair, mutagenesis or damage tolerance. Within the IGC you will be co-supervised by biochemist Dr Tom Deegan.

Key Responsibilities & Requirements:

The successful candidate will have experience in molecular biology and nucleic acid manipulation along with core biochemistry techniques including protein purification. You will have ownership of your own projects and work closely with experts in the analysis of high-throughput sequencing and mass-spectrometry data, familiarity with such platforms would be an advantage.

The post holder will have many opportunities for multidisciplinary collaborative working both within the IGC and with CAUSE partners based at the Sanger Institute, Hubrecht Institute, Harvard University, University of San Diego and University of Minnesota. The wider Cancer Grand Challenge community will also provide excellent opportunities for training, professional and network development.

Eligibility:

Applicants must have a PhD in molecular biology, biochemistry or a related discipline for appointment at Research Associate level. Applicants close to completion of their PhDs will also be considered where experience is directly relevant. Please see the job description and person specification document associated with this advert for the full list of criteria.

Contract & Working Conditions:

This post is full-time (35 hours per week); however, we are open to considering part-time or flexible working patterns. Initially a 24-month contract is offered, with the possibility of extension.

Application Process:

Please include the following documents in your application:

CV either narrative or structured.
Cover letter explaining your fit for the role, the science that excites you how you think this role could help realise your aspirations.

About The University of Edinburgh:

The University of Edinburgh is a world-class organisation. We look for the best in the field across all disciplines and provide a working environment where academics can develop their careers and passion for their chosen subject area.

The University isn t just any employer. We are part of a local community and a contributor to global thinking, progress and research. In Edinburgh, you are in one of the world s most attractive cities with active arts and social sectors, while working in a University that has made significant contributions to society, medicine, physics and teaching for over four centuries. Our people have helped create the modern world and are working on more ground-breaking technologies and practices.

Staff Benefits:

As a valued member of our team, you can expect:

A competitive salary.
An exciting, positive, creative, challenging and rewarding place to work.
To be part of a diverse and vibrant international community.
Comprehensive Staff Benefits, including generous annual leave entitlement, a defined benefits pension scheme, a wide range of staff discounts, family-friendly initiatives, and flexible work options. Check out the full list on our staff benefits page and use our reward calculator to discover the value of your pay and benefits.

Equality, Diversity, and Inclusion:

The University of Edinburgh holds a Silver Athena SWAN award in recognition of our commitment to advance gender equality in higher education.

We are members of the Race Equality Charter, and we are also Stonewall Scotland Diversity Champions, actively promoting LGBT equality.

We welcome applications from all qualified candidates and aim to make appointments only on the criteria of merit and evidence.

Right to Work:

Prior to any employment commencing with the University, you will be required to evidence your right to work in the UK. Further information is available on our right to work webpages.

The University may be able to sponsor the employment of international workers in this role. This will depend on a number of factors specific to the successful applicant.

About Us:

As a world-leading research-intensive University, we are here to address tomorrow s greatest challenges. Between now and 2030 we will do that with a values-led approach to teaching, research and innovation, and through the strength of our relationships, both locally and globally.

About the Team:

The School of Genetics and Cancer is one of the six Schools that make up the College of Medicine and Veterinary Medicine (CMVM). The School is home to the Institute of Genetics and Cancer (IGC) whose goals are to carry out excellent genetic, genomic, cellular and clinical science, so that we contribute significantly to the understanding of human development, physiology and disease, and apply this knowledge for the benefit of patients and society. The IGC is one of the College s five world-leading research institutes. The teams in the six CMVM Schools work together to build outstanding discovery and translational research programmes designed to answer the major challenges facing humanity, animal and planetary health, now and in the future. The College s undergraduate and postgraduate teaching is delivered through Edinburgh Medical School and the Royal (Dick) School of Medical Studies with contributions from all six schools.

To find out more visit: School of Genetics and Cancer webpage ( https://medicine-vet-medicine.ed.ac.uk/school-of-genetics-and-cancer ) (opens a new browser tab).